Dogoteka DogoMaxy – 60 Stück

Dietary complementary feed* in tablets for large breed dogs, useful for supporting joint metabolism in case of osteoarthritis.*Feed with particular nutritional or dietary purposes.Enhanced formula with the addition of fish oil.SUPPORT FOR THE JOINTS OF DOGS FROM ADULT AGE OR LARGE DOGS PREDISPOSED TO CARTILAGE WEAR.Active ingredients: GLUCOSAMINE and CHONDROITIN SULFATE – it is called glucosamine sulphate and the result of Italian research is the substance that has shown – for the first time in the world – to intervene on the process of ‘wear and tear’ of the joints both in older dogs and in dogs that practice sports. Normally in the body, glucosamine is present in the joints, synovial fluid, tendons, ligaments and muscles and is synthesized by glucose In some situations where there may be a deficiency of glucosamine produced naturally by the body, a ‘exogenous contribution through eg. the intake of complementary feeds. The administration of glucosamine and chondroitin sulfate to puppies and large or elderly dogs can be particularly useful for strengthening and chondroprotection of bone and cartilage structures. Glucosamine from exogenous intake is obtained from the hydrolysis of chitin, obtained from the shells of some crustaceans (marine exoskeletons). Chondroitin sulfate, as well as hyaluronic acid, belongs to a family of heteropolysaccharides called glycosaminoglycans or GAGs. They, in the form of proteoglycans, form the basic substance of the extracellular matrix of the connective tissue. Chondroitin sulfate is made up of repetitive linear units consisting of N-acetylgalactosamine and D-glucuronic acid. Chondroitin sulfate is found in cartilage. Chondroitin sulfate, especially in combination with glucosamine, can promote and therefore maintain the structure of cartilage (chondroprotection). In particular – attracts water into the cartilage tissue. Articular cartilage is not a vascularized tissue; the nutrients are supplied to it through a liquid called synovial fluid, or synovium, which, in addition to supplying this tissue, also has a cushioning function, that is, to reduce friction between two bone ends. Synovial fluid consists mainly of water, hyaluronic acid and glycoproteins, therefore hydration of the synovial fluid is of fundamental importance. EFFECTS OF GARCINIA MANGOSTANA – garcinia mangostana is a typical fruit of various areas of South East Asia. In the late 1990s, scientists isolated the Xanthones from the Mangosteen fruit. The class of xanthones, polyphenols derived from Benzo-y-pyrone, has many properties, the most interesting are represented by the high antioxidant power of gamma mangostin. Garcinia mangostana acts as a joint protector. BIOCELL COLLAGEN® – it is a mixer of substances: type II hydrolyzed collagen, hyaluronic acid, chondroitin sulfate, essential amino acids. Collagen, the main protein of connective tissue, is essential for structuring the joints, tendons and ligaments. Type II collagen is the most common type of collagen found in joint cartilages and accounts for 80-90% of the total collagen content. Biocell collagen contains hydrolyzed collagen, obtained using a patented technology that allows the extraction of a high percentage of collagen II, hyaluronic acid and chondroitin sulfate, essential components of the body’s structure. This hydrolyzed collagen is formed by a molecular structure that allows for prompt assimilation. DEVIL’S CLAW LONGA CURCUMA L PROTRIXAN® – a blend for exclusive use in the Dogoteka veterinary line, which brings together in a balanced and synergistic form components of natural origin, extensively studied and validated by international scientific literature. Protrixan® is a mix made up of dry extract of Garcinia cambogia, Garcinia mangostana powder and Turmeric powder, which promotes joint function and acts as an antioxidant. Bibliografia: Lih-Geen Chen, Ling-Ling Yang, Ching-Chiung Wang; “Anti-infammatory activity of mangostins from Garcinia mangostana” Food and Chemical Toxicolgy; 46: 688-693, 2008 Keigo Nakatani, Masanori Atsumi, Tsutomu Arakawa, Kenji Oosawa, Susumu Shimura, Norimichi Nakahata and Yasushi Ohizumi; “Inibitions of Histamine Release and Prostaglandin E2 Syntesis by Mangosteen, a Thai Medicinal Plant” Biological & Pharmaceutical Bullettin; 25(9): 1137-1141, 2002) José Pedraza-Chaverri, Noemí Cárdenas-Rodríguez, Marisol Orozco-Ibarra, Jazmin M. Pérez-Rojas;“Medicinal properties of mangosteen (Garcinia mangostana)” Food and Chemical Toxicology, in press; doi:10.1016/j.fct.2008.07.024, 2008 Yoshikawa M., Harada E., Miki A., Tsukamoto K., Si Qian L., Yamahara J., Murakami N. 1994. Antioxidant constituents from the fruit hulls of mangosteen (Garcinia mangostana L.) originatin in Vietnam. Yakugaku Zasshi 114, 129-133